Investigadoras/es
Grupo de investigación
Modelado Molecular de Sistemas de Interés Biológico
Función en el grupo: Director
Publicaciones seleccionadas
M. Richezzi, J. Ferreyra, J. Puzzolo, L. Milesi, C. M. Palopoli, D. M. Moreno, C. Hureau, S. R. Signorella. “Versatile Activity of a Copper(II) Complex Bearing a N4-Tetradentate Schiff Base Ligand with Reduced Oxygen Species” European Journal of Inorganic Chemistry, 2022, e202101042 DOI: 10.1002/ejic.202101042
P. Hinchliffe, D. M. Moreno, M. A. Rossi, M. F. Mojica, V. Martinez, Valentina Villamil, B. Spellberg, G. L. Drusano, C. Banchio, G. Mahler, R. A. Bonomo, A. J. Vila, and J. Spencer, “2‑Mercaptomethyl Thiazolidines (MMTZs) Inhibit All Metallo-β-2 Lactamase Classes by Maintaining a Conserved Binding Mode”, ACS Infect. Dis., 2021, 7, 9, 2697–2706 https://doi.org/10.1021/acsinfecdis.1c00194
F. Cortés Rodríguez, G. Frattini, L. F. Krapp, H. Martinez-Hung, D. M. Moreno, M. Roldán, J. Salomón, L. Stemkoski, S. Traeger, M. Dal Peraro, and L. A. Abriata, “MoleculARweb: A Web Site for Chemistry and Structural Biology Education through Interactive Augmented Reality out of the Box in Commodity Devices” J. Chem. Educ., 2021, 98, 7, 2243–2255 https://doi.org/10.1021/acs.jchemed.1c00179
M. A. Rossi, V. Martinez, P. Hinchliffe, M. F. Mojica, V. Castillo, D, M. Moreno, R, Smith, B,d Spellberg, G, L. Drusano, C, Banchio, R, A. Bonomo, J, Spencer, A. J. Vila* and G. Mahler*, 2-Mercaptomethyl-thiazolidines use conserved aromatic–S interactions to achieve broad-range inhibition of metallo-β-lactamases†, Chem. Sci., 2021, 12, 2898–2908 https://doi.org/10.1039/D0SC05172A
A.M.L. Rojas, S.I. Drusin, U. Chorostecki, J.L. Mateos, B.Moro, N.G. Bologna, E. G. Bresso, A. Schapire, R.M. Rasia, D.M. Moreno, and J.F. Palatnik, “Identification of key sequence features required for microRNA biogenesis in plants” Nature Comm., 2020, 11:5320 https://doi.org/10.1038/s41467-020-19129
M. I. Osella, M. O. Salazar, M. D. Gamarra, D. M. Moreno, F. Lambertucci, D. E. Frances, R. L. E. Furlan. “Arylsulfonyl histamine derivatives as powerful and selective α-glucosidase inhibitors†” RSC Med. Chem., 2020, 11, 518-527 https://doi.org/10.1039/C9MD00559E
S I. Drusin, R M. Rasia, D. M. Moreno* “Study of the role of Mg2+ in dsRNA processing mechanism by bacterial RNase III through QM/MM simulations” Journal of Biological Inorganic Chemistry, 2020, 25, 89–98 https://doi.org/10.1007/s00775-019-01741-7
J. L. Puzzolo, S. I. Drusin, V. A. Daier, S. Signorella and Diego M. Moreno* “Using theoretical calculations to predict the redox potential of mononuclear manganese complexes”, New J. Chem, 2018, 42, 14827-14831 https://doi.org/10.1039/C8NJ03254H
L. J. González, C. Stival, J. L. Puzzolo, D. M. Moreno, and A. J. Vila. “Mechanisms of Resistance Shaping Substrate Selectivity in a Broad-Spectrum Metallo-β-Lactamase”. Antimicrob. Agents Chemother., 2018; 62:4 https://doi.org/10.1128/AAC.02079-17
M.N. Lisa, A.R. Palacios, M. Aitha, M.M. González, Diego M. Moreno, Michael W. Crowder, Robert A. Bonomo, James Spencer, David L. Tierney, , Leticia I. Llarrull and Alejandro J. Vila., “A General Reaction Mechanism for Ca arbapenem Hydrolysis by Mono‐ and Binuclear Metallo-β‐lactamases.”, Nature Comm., 2017, 8:538, https://doi.org/10.1038/s41467-017-00601-9
Curriculum Vitae
Formación Académica
- Lic. En Química (FBIOyF-UNR, 2004)
- Doctor en Ciencias Químicas FBIOyF-UNR, 2009)
Cargos Actuales
- Investigador independiente CONICET
- Profesor Adjunto FBIOyF-UNR
Formación RRHH
1 tesis finalizadas.
2 tesis en curso.
2 trabajos finales de grado finalizados.
3 trabajos finales de grado en curso.
Extensión/Gestión actuales:
Secretario de Ciencia y Tecnología (FBIOyF-UNR, 2020-continua)
Publicaciones
27 artículos
3 libros
1 capítulo de libro
numerosos congresos
Subsidios vigentes
PICT-2020-SERIEA-03769. Periodo: 2022-2024. ANPCyT. Director
PIP 2021-2023. CONICET. Integrante
PICT 2019-2019-03276. Período: 2021-2023. ANPCyT. Co-Director
BIO551. Período: 2018-2022. Universidad Nacional de Rosario. Director